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Glossary Homeostasis

process of maintaining stable internal conditions in organisms

Homeostasis is the process by which living organisms maintain a stable internal environment despite changes in external conditions. This involves various physiological mechanisms that regulate factors like temperature, pH, and electrolyte balance to ensure optimal functioning of cells and organs. For example, the human body sweats to cool down when it's hot, helping to keep the internal temperature within a narrow, healthy range.

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research Epidermal homeostasis: a balancing act of stem cells in the skin

1039 citations , February 2009 in “Nature Reviews Molecular Cell Biology”

This review discusses the reuse of molecular mechanisms involved in embryonic skin development for maintaining adult epidermal homeostasis and reports no new results.

research Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair

265 citations , July 2012 in “Cell”

This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.

research Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

181 citations , January 2019 in “Cell”

In this research, authors found that skin-resident ILCs regulate sebaceous gland function and microbial balance, emphasizing an immune-epithelia system that supports host-microbe symbiosis.

research Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer

124 citations , February 2018 in “Nature Reviews Genetics”

This review covers recent findings on stem cell plasticity under normal and cancerous conditions but presents no new experimental results, highlighting implications for regenerative medicine and cancer treatments.

research Homeostasis of the sebaceous gland and mechanisms of acne pathogenesis

82 citations , May 2019 in “British Journal of Dermatology”

This review discusses various hormones and signaling pathways involved in sebaceous gland homeostasis and their potential impact on acne pathogenesis, but it reports no new experimental findings.

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