Comparing the Effectiveness of Local Solution of Minoxidil and Caffeine 2.5% with Local Solution of Minoxidil 2.5% in Treatment of Androgenetic Alopecia

    November 2013 in “ Journal of Mazandaran University of Medical Sciences ”
    Masoud Golpour, Hossein Rabbani, Davoud Farzin, Fariborz Azizi
    Studysummary This study found that a topical solution of caffeine and minoxidil 2.5% was more effective in treating androgenetic alopecia than minoxidil 2.5% alone.
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    Research cited in this study 10

    1. Caffeine’s Mechanisms of Action and Its Cosmetic Use Skin Pharmacology and Physiology · 2012
    2. Evidence-Based Clinical Guidelines for Treatment: Acne and Androgenetic Alopecia Journal of Dermatology and Cosmetic · 2012
    3. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men Journal der Deutschen Dermatologischen Gesellschaft · 2011
    4. Permeation of Topically Applied Caffeine Through Human Skin – A Comparison of In Vivo and In Vitro Data BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology · 2009
    5. Follicular Penetration of Topically Applied Caffeine via a Shampoo Formulation Skin Pharmacology and Physiology · 2007
    6. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    7. Androgenetic Alopecia in Men and Women Clinics in Dermatology · 2001
    8. Immunohistochemical Localization of Types 1 and 2 5α-Reductase in Human Scalp British Journal of Dermatology · 1999
    9. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    10. Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996

    Related research 19

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    5. A Randomized Controlled, Single-Observer Blinded Study to Determine the Efficacy of Topical Minoxidil Plus Microneedling Versus Topical Minoxidil Alone in the Treatment of Androgenetic Alopecia Journal of Cutaneous and Aesthetic Surgery · 2018
    6. The Clinical Effect of JetPeel-Assisted Topical Minoxidil in the Treatment of Androgenetic Alopecia: A Randomized Pilot Study Journal of Cosmetic and Laser Therapy · 2017
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    8. An Open Label, Multi-Center Clinical Trial of Topical 5% Minoxidil Solution for the Treatment of Male Androgenetic Alopecia (A Phase IV Study) Journal of Clinical Dermatology · 2009
    9. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    10. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    11. Comparative Efficacy of Various Treatment Regimens for Androgenetic Alopecia in Men Journal of Dermatology · 2002
    12. Improvement in Androgenetic Alopecia (Stage V) Using Topical Minoxidil in a Retinoid Vehicle and Oral Finasteride Archives of Dermatology · 1995
    13. Treatment of Male Pattern Alopecia Using Topical Minoxidil in The Netherlands International Journal of Dermatology · 1988
    14. Androgenetic Alopecia Treated With Topical Minoxidil Journal of The American Academy of Dermatology · 1987
    15. Long-Term Efficacy of Topical Minoxidil in Male Pattern Baldness Journal of The American Academy of Dermatology · 1987
    16. Long-Term Follow-Up of Men with Male Pattern Baldness Treated with Topical Minoxidil Journal of The American Academy of Dermatology · 1987
    17. Dose-Response Study of Topical Minoxidil in Male Pattern Alopecia Journal of The American Academy of Dermatology · 1987
    18. Dose-Response Study of Topical Minoxidil in Male Pattern Baldness Journal of The American Academy of Dermatology · 1986
    19. Topical Minoxidil Dose-Response Effect in Alopecia Areata Archives of Dermatology · 1986