Treatment of Male Pattern Alopecia Using Topical Minoxidil in The Netherlands

July 1988 in “ International Journal of Dermatology ”

R. O. G. M. Dutrée‐Meulenberg, C. Nieboer, F. H. J. Koedijk, E Stolz

minoxidil male pattern alopecia placebo hair count topical solution Rogaine

Studysummary This study found that 2% minoxidil solution was about three times more effective than a placebo in improving hair growth in men with early male pattern alopecia over 24 weeks.

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This 1988 study conducted in The Netherlands evaluated the efficacy and safety of a 2% minoxidil solution compared to a placebo in treating early male pattern alopecia over 24 weeks. A total of 144 male patients participated, applying 1 ml of either the minoxidil or placebo solution twice daily. The results showed that the 2% minoxidil solution was approximately three times more effective than the placebo in improving hair count and subjective evaluations by both investigators and patients. The study found no significant effects of minoxidil on blood pressure, pulse rate, or body weight. One participant in the placebo group withdrew due to a skin rash. Overall, the study supported the safe and effective use of minoxidil for early male pattern alopecia.

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Research cited in this study

8 / 8 results

research Dose-Response Study of Topical Minoxidil in Male Pattern Baldness

58 citations , July 1986 in “Journal of The American Academy of Dermatology”

Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.

research Topical Minoxidil Useful in 18% of Patients with Androgenetic Alopecia: A Study of 430 Cases

16 citations , January 1986 in “Dermatology”

In this study, 1% minoxidil lotion led to good results in 18% of male patients with androgenetic alopecia, but only 6% maintained regrowth one year after stopping treatment.

research Topical Minoxidil in Early Male Pattern Baldness

138 citations , August 1985 in “Journal of The American Academy of Dermatology”

Minoxidil promotes hair growth in male pattern baldness.

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

55 citations , February 1985 in “Archives of Dermatology”

In this randomized trial, topical minoxidil treatment resulted in cosmetically acceptable hair growth in 32% of men with hereditary male pattern baldness, with no serious side effects reported.

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

55 citations , February 1985 in “Archives of Dermatology”

This study found that 32% of patients with hereditary male pattern baldness experienced cosmetically acceptable hair growth after applying topical minoxidil twice daily, with no serious side effects reported.

research Topical Minoxidil for Hair Regrowth

80 citations , September 1984 in “Journal of The American Academy of Dermatology”

In this study, 5% topical minoxidil was observed to promote hair regrowth in some patients with androgenic alopecia, while no regrowth was noted in patients with alopecia areata.

research Reversal of Baldness in Patient Receiving Minoxidil for Hypertension

95 citations , December 1980 in “The New England Journal of Medicine”

Minoxidil helped bald patient regrow hair.

research Treatment of Severe Hypertension with Minoxidil: Advantages and Limitations

37 citations , April 1979 in “The Journal of Clinical Pharmacology”

Minoxidil effectively controls blood pressure but side effects may limit its use.