Treatment of Male Pattern Alopecia Using Topical Minoxidil in The Netherlands

July 1988 in “ International Journal of Dermatology ”

R. O. G. M. Dutrée‐Meulenberg, C. Nieboer, F. H. J. Koedijk, E Stolz

TLDR Minoxidil is safe and effectively increases hair growth in early male pattern baldness.

This 1988 study conducted in The Netherlands evaluated the efficacy and safety of a 2% minoxidil solution compared to a placebo in treating early male pattern alopecia over 24 weeks. A total of 144 male patients participated, applying 1 ml of either the minoxidil or placebo solution twice daily. The results showed that the 2% minoxidil solution was approximately three times more effective than the placebo in improving hair count and subjective evaluations by both investigators and patients. The study found no significant effects of minoxidil on blood pressure, pulse rate, or body weight. One participant in the placebo group withdrew due to a skin rash. Overall, the study supported the safe and effective use of minoxidil for early male pattern alopecia.

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Research cited in this study

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Treatment of Male Pattern Alopecia Using Topical Minoxidil in The Netherlands

Research cited in this study

research Dose-Response Study of Topical Minoxidil in Male Pattern Baldness

research Topical Minoxidil Useful in 18% of Patients with Androgenetic Alopecia: A Study of 430 Cases

research Topical Minoxidil in Early Male Pattern Baldness

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research Reversal of Baldness in Patient Receiving Minoxidil for Hypertension

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