A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia

July 1996 in “ Journal of The American Academy of Dermatology ”

Madeleine Duvic, Noreen A. Lemak, Vicente Valero, Sharon R. Hymes, Kathryn L. Farmer, Gabriel N. Hortobagyi, Ronald J. Trancik, B. Bandstra, Linda D. Compton

minoxidil chemotherapy-induced alopecia topical solution adjuvant chemotherapy Rogaine

TLDR Minoxidil shortens baldness from chemotherapy by 50.2 days without significant side effects.

A study from 26 years ago investigated the effectiveness and safety of minoxidil in reducing hair loss caused by chemotherapy. The study involved 22 women undergoing adjuvant chemotherapy after breast surgery who were randomly assigned to use a 2% minoxidil topical solution or a placebo. The results showed that the period of baldness was shortened by a mean of 50.2 days in the minoxidil group, and there were no significant side effects. The study suggests that minoxidil can decrease the duration of alopecia caused by chemotherapy.

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Research cited in this study

7 / 7 results

research Minoxidil as a Prophylaxis of Doxorubicin-Induced Alopecia

49 citations, October 1994 in “Annals of Oncology”

Minoxidil not effective in preventing chemotherapy-induced hair loss.

research Topical Minoxidil Useful in 18% of Patients with Androgenetic Alopecia: A Study of 430 Cases

16 citations, July 1986 in “Dermatology”

Using minoxidil lotion for hair regrowth in androgenetic alopecia has limited success and should be evaluated carefully.

research Review: Topical Minoxidil for Male Pattern Baldness

25 citations, May 1986 in “The American Journal of the Medical Sciences”

Minoxidil helps hair growth and boosts self-esteem in balding men.

research Topical Minoxidil Dose-Response Effect in Alopecia Areata

54 citations, February 1986 in “Archives of Dermatology”

Higher minoxidil concentration (5%) works better for severe hair loss, with most patients seeing regrowth in 48-60 weeks.

research Topical Minoxidil Therapy and Hair Regrowth

20 citations, February 1985 in “Archives of Dermatology”

Minoxidil helps hair regrowth, especially with more indeterminate hairs.

research Percutaneous Absorption of Minoxidil in Humans

52 citations, February 1985 in “Archives of Dermatology”

Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

55 citations, February 1985 in “Archives of Dermatology”

Using minoxidil on the scalp can help grow hair for people with hereditary baldness.

Related Research

6 / 6 results

research Ethnopharmacological Review of Medicinal Plants for the Treatment of Alopecia

March 2023 in “International Journal of Advanced Research in Science, Communication and Technology”

Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.

research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss

1 citations, October 2022 in “PubMed”

Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.

research Baricitinib Results in Eyebrow and Eyelash Growth in Patients With Alopecia Areata Who Do Not Achieve 20% or Less Scalp Hair Loss

1 citations, September 2022 in “Journal of The American Academy of Dermatology”

Baricitinib helps grow eyebrows and eyelashes in severe alopecia areata patients.

research Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil

1 citations, August 2022 in “JAAD case reports”

Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.

research Disorders of Hair

July 2013 in “DeckerMed Medicine”

The document's conclusion cannot be provided because the document is not readable or understandable.

research Use of Topical Minoxidil Therapy for Androgenetic Alopecia in Women

58 citations, October 1993 in “International Journal of Dermatology”

Minoxidil helps hair growth and reduces shedding in women.

A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia

Research cited in this study

research Minoxidil as a Prophylaxis of Doxorubicin-Induced Alopecia

research Topical Minoxidil Useful in 18% of Patients with Androgenetic Alopecia: A Study of 430 Cases

research Review: Topical Minoxidil for Male Pattern Baldness

research Topical Minoxidil Dose-Response Effect in Alopecia Areata

research Topical Minoxidil Therapy and Hair Regrowth

research Percutaneous Absorption of Minoxidil in Humans

research Topical Minoxidil Therapy in Hereditary Androgenetic Alopecia

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