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GlossaryTetrahydrocannabinol

primary psychoactive compound in cannabis, often called THC

Tetrahydrocannabinol, commonly known as THC or Δ9-THC, is the primary psychoactive compound found in cannabis. It interacts with the endocannabinoid system in the brain, particularly the CB1 receptors, to produce effects such as euphoria, altered perception, and relaxation.

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research Segmental Hair Analysis for 11-Nor-9-Tetrahydrocannabinol-9-Carboxylic Acid and the Patterns of Cannabis Use

30 citations , March 2012 in “Journal of Analytical Toxicology”

THCCOOH levels in hair decrease from root to tip and don't match well with self-reported cannabis use.

research Mechanism of Cannabinoid Incorporation in Hair

December 2018 in “J. Willard Marriott Library”

Cannabinoids like THC and THCA get into hair through skin oils, not hair color.

Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases

research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases

3 citations , December 2022 in “Cells”

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

The Impact of Cannabis Use on Local Anesthetic Dosing During Hair Restoration Surgery: A Case Report, Proposed Mechanisms, and Clinical Recommendations

research The Impact of Cannabis Use on Local Anesthetic Dosing During Hair Restoration Surgery: A Case Report, Proposed Mechanisms, and Clinical Recommendations

March 2025 in “Journal of Dermatological Treatment”

Cannabis users may need higher anesthetic doses during hair restoration surgery.

Improved Forensic Hair Evidence for Drugs of Abuse by Mass Spectrometry

research Improved Forensic Hair Evidence for Drugs of Abuse by Mass Spectrometry

June 2016

Forensic hair analysis for drugs is now more reliable and accurate.

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