Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis

    Anik Gupta, Rachel R. Mays, M. S. Dotzert, Sarah G Versteeg, Neil H. Shear, Vincent Piguet
    From the encyclopedia
    Low Level Laser Therapy →

    laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

    Platelet-Rich Plasma →

    growth factors taken from your blood and injected into your scalp to stimulate hair

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

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    Studysummary This study found that low-level laser therapy was the most effective non-surgical treatment for androgenetic alopecia, although the overall quality of evidence supporting various therapies was generally low. Our plain-language summary of this paper — not a Tressless recommendation.
    A systematic review and network meta-analysis of non-surgical treatments for androgenetic alopecia (AGA) found that low level laser therapy (LLLT) was the most effective treatment, followed by PRP, finasteride, and minoxidil. However, the quality of evidence was generally low, and more high-quality trials are needed to support these findings. Finasteride and minoxidil were found to be the most effective non-surgical treatments for hair regrowth in patients with AGA, while platelet-rich plasma and low-level laser therapy showed some promise but require further research. The study suggests that quantitative comparisons of non-surgical AGA treatments could aid treatment decisions and influence patient outcomes.
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