Meta-Analysis of Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia

January 2017 in “ Journal of Dermatological Treatment ”

Anik Gupta, Jessie Carviel

platelet-rich plasma androgenetic alopecia growth factors cell survival proliferation differentiation vascularization angiogenesis PRP AGA

TLDR PRP therapy may effectively treat hair loss, but more research needed.

This document is a meta-analysis of studies on the efficacy of platelet-rich plasma (PRP) therapy for androgenetic alopecia (AGA). The study concludes that PRP may be an effective treatment for AGA, but further research is needed to refine treatment protocols and establish it as an approved therapy. The overall standardized mean difference was 0.51 in favor of PRP treatment when compared to baseline. PRP is a rich source of growth factors that can stimulate cell survival, proliferation, differentiation, vascularization, and angiogenesis.

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research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations , September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia

74 citations , July 2015 in “Asian Journal of Transfusion Science”

Platelet-rich plasma (PRP) injections can effectively increase hair density and thickness in people with androgenic alopecia, without major side effects.

research Autologous Platelet-Rich Plasma as a Treatment for Male Androgenetic Alopecia: Study of 14 Cases

4 citations , June 2015 in “Journal of clinical & experimental dermatology research”

PRP injections may slightly improve hair density and count for male hair loss, but more research is needed.

research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

70 citations , February 2015 in “Expert Opinion on Drug Discovery”

Topical drugs and near-infrared light therapy show potential for treating alopecia.

research Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss

54 citations , January 2015 in “Wound Repair and Regeneration”

PRP injections may improve hair thickness and density in female hair loss patients.

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations , October 2014 in “Journal of Cutaneous and Aesthetic Surgery”

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

research Platelet-Rich Plasma for Androgenetic Alopecia

107 citations , September 2014 in “Dermatologic Surgery”

PRP injections improve hair thickness for baldness.

research Platelet-Rich Plasma in Dermatology: Boon or Bane?

119 citations , January 2014 in “Indian Journal of Dermatology, Venereology and Leprology”

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

research Platelet-Rich Plasma in Androgenic Alopecia: Myth or Effective Tool

115 citations , January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

183 citations , January 2014 in “BioMed Research International”

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study

88 citations , January 2014 in “Journal of The European Academy of Dermatology and Venereology”

Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.

research Promotional Effect of Platelet-Rich Plasma on Hair Follicle Reconstitution In Vivo

63 citations , December 2013 in “Dermatologic Surgery”

Platelet-Rich Plasma (PRP) increases the number of new hair follicles and speeds up hair formation.

research A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

205 citations , August 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research Hair Growth and Rejuvenation: An Overview

81 citations , June 2010 in “Journal of Dermatological Treatment”

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

research A Mouse Model of Androgenetic Alopecia

42 citations , May 2010 in “Endocrinology”

Mice with human gene experienced hair loss when treated with DHT.

research Pitx2, A β-Catenin-Regulated Transcription Factor, Regulates The Differentiation Of Outer Root Sheath Cells Cultured In Vitro

51 citations , April 2009 in “Journal of dermatological science”

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

research Promotive Effect of Minoxidil Combined with All-Trans Retinoic Acid (Tretinoin) on Human Hair Growth In Vitro

41 citations , April 2007 in “Journal of Korean Medical Science”

Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , November 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.