Novel Versus Modified Platelet-Rich Plasma Therapy for Hair Loss Treatment: A Systematic Review and Meta-Analysis

May 2023

Kaneez Fatima, Haziq Ovais, Zainab Anwar, Maaz Abdul Latif Motan, Maaz Masood Khan, Aly Hamza Khowaja, Altamash Shahriyar Ghazanfar, Muhammad Ahmed Khalid, Ayesha Jamil, Yahya Ismail Mujtaba, Sahil Kumar, Ahmed Mustafa Rashid

platelet-rich plasma PRP androgenic alopecia AGA hair density placebo combination therapies

TLDR Stand-alone PRP therapy effectively increases hair density for hair loss treatment.

This systematic review and meta-analysis compared the effectiveness of stand-alone platelet-rich plasma (PRP) therapy versus PRP combined with other treatments for androgenic alopecia (AGA). Analyzing data from 9 studies involving 230 individuals, the study found that both stand-alone PRP and PRP combination therapies significantly increased hair density compared to placebo, with mean differences (MD) of 25.39 and 34.38, respectively. However, the results did not justify the superiority of PRP-combined therapy over stand-alone PRP. The study concludes that stand-alone PRP therapy should be included in treatment protocols for AGA, while further research is needed to validate the efficacy of combination therapies.

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