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Glossary Dermatomyositis

inflammatory disease causing muscle weakness and skin rash

Dermatomyositis is an inflammatory disease characterized by muscle weakness and a distinctive skin rash. It involves the immune system attacking the body's own tissues, leading to symptoms such as muscle pain, fatigue, and red or purple rashes, often on the face, knuckles, and other areas. This condition can also be associated with other autoimmune disorders and may require treatments like corticosteroids or immunosuppressive drugs to manage symptoms.

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research An unusual presentation of dermatomyositis: The type Wong variant revisited

36 citations , November 2000 in “Journal of the American Academy of Dermatology”

This case study describes a unique patient with dermatomyositis who exhibited features of pityriasis rubra pilaris and porokeratosis, suggesting markers for malignancy warranting thorough investigation and monitoring.

research Horizontal and vertical sections of scalp biopsy specimens from dermatomyositis patients with scalp involvement

16 citations , February 2018 in “Journal of The American Academy of Dermatology”

This study found that scalp involvement in dermatomyositis consistently shows a nonscarring pattern with chronic telogen effluvium, featuring telangiectasia and mucin deposition as universal histologic markers.

research Understanding the Role of Type I Interferons in Cutaneous Lupus and Dermatomyositis: Toward Better Therapeutics

14 citations , September 2024 in “Arthritis & Rheumatology”

In this study, a patient with clinically amyopathic dermatomyositis experienced persistent skin issues despite treatment, highlighting questions about type I interferon's role in skin disorders and potential IFN-targeted therapies for cutaneous lupus erythematosus and dermatomyositis.

research Trichoscopic Signs in Dermatomyositis, Systemic Lupus Erythematosus, and Systemic Sclerosis: A Comparative Study of 150 Patients

12 citations , December 2021 in “Dermatology”

This study found that trichoscopy can differentiate between dermatomyositis, systemic lupus erythematosus, and systemic sclerosis by identifying distinctive features and may help assess disease activity.

research An unusual presentation of dermatomyositis: The type Wong variant revisited

9 citations , November 2000 in “Journal of the American Academy of Dermatology”

This report presents a rare case of a patient with type Wong dermatomyositis who also exhibits clinical and histologic features of porokeratosis, potentially signaling associated malignancies in dermatomyositis patients.

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