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    GlossaryDermal Mucin

    gel-like substance in skin's dermis aiding hydration and elasticity

    Dermal mucin refers to a gel-like substance composed of glycosaminoglycans, primarily hyaluronic acid, found within the dermis layer of the skin. It plays a crucial role in maintaining skin hydration, elasticity, and structural integrity. In certain skin conditions, such as lupus or dermatomyositis, an abnormal accumulation of dermal mucin can occur, leading to skin swelling and other symptoms.

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      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

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      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      commercial product with a blend of mostly natural ingredients for hair regrowth

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Haircafe on why microneedling is bad for hair growth

      in Microneedling  157 upvotes 3 months ago
      Microneedling combined with minoxidil and finasteride shows significant hair regrowth, though opinions on its effectiveness vary. Some users report substantial benefits, while others highlight the need for more research and consistency in application.

      community Follow me on my laser hair growth journey.

      in Progress Pictures  37 upvotes 5 months ago
      A 34-year-old male documents his hair growth journey using the iRestore Elite laser cap, biotin, and Pure Synergy Organic Superfood Capsules, after unsuccessful hair transplant and previous treatments with minoxidil and finasteride. Replies suggest using finasteride or dutasteride instead and caution against excessive use of the laser cap.