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Glossary Dermal Mucin

gel-like substance in skin's dermis aiding hydration and elasticity

Dermal mucin refers to a gel-like substance composed of glycosaminoglycans, primarily hyaluronic acid, found within the dermis layer of the skin. It plays a crucial role in maintaining skin hydration, elasticity, and structural integrity. In certain skin conditions, such as lupus or dermatomyositis, an abnormal accumulation of dermal mucin can occur, leading to skin swelling and other symptoms.

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Research

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research Dermal mucin in alopecia areata – tell tale sign or incidental finding?

10 citations , July 2008 in “Journal of Cutaneous Pathology”

This study reports that marked, deep dermal mucin deposition in a patient with alopecia areata may indicate underlying systemic lupus erythematosus, as this feature was not prevalent in other alopecia areata cases.

research Dermal Mucinosis in the Eosinophilia-Myalgia Syndrome

8 citations , November 1990 in “Archives of Dermatology”

This case report details a woman with eosinophilia-myalgia syndrome associated with L-tryptophan ingestion, highlighting skin lesions with abundant dermal mucin.

research Follicular Mucinosis (Alopecia Mucinosa)

20 citations , June 1964 in “Archives of Dermatology”

This study described three cases of follicular mucinosis and observed that one case responded rapidly to systemic corticosteroids, suggesting a potential therapeutic effect.

research Cutaneous Focal Mucinosis: A Case Report

18 citations , January 2002 in “Pediatric Dermatology”

This case report describes a rare instance of cutaneous focal mucinosis in a 12-year-old Chinese girl, presented as a hypopigmented plaque on her chin.

research A Case of Cutaneous Focal Mucinosis With Follicular Induction

1 citations , February 2017 in “The American journal of dermatopathology/American journal of dermatopathology”

This case report presented a 52-year-old man with cutaneous focal mucinosis, exhibiting rare follicular induction of the epidermis, underscoring the importance of recognizing this association in differential diagnoses.

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Community Join

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community 17M - beat the norwood reaper in 4 months. Am I a hyper responder? Can I maintain for a year until I can start fin?

in Progress Pictures 725 upvotes 1 year ago

A 17-year-old improved his hairline using minoxidil and derma stamping, planning to start finasteride at 18. He received advice on dosing and potential side effects to maintain results.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community Haircafe on why microneedling is bad for hair growth

in Microneedling 157 upvotes 2 years ago

Microneedling combined with minoxidil and finasteride shows significant hair regrowth, though opinions on its effectiveness vary. Some users report substantial benefits, while others highlight the need for more research and consistency in application.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

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