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Glossary Dermal

layer beneath the epidermis containing blood vessels and hair follicles

The term "dermal" refers to anything related to the dermis, which is the thick layer of living tissue below the outer epidermis of the skin. The dermis contains blood vessels, hair follicles, sweat glands, and connective tissue, playing a crucial role in skin health, sensation, and thermoregulation.

Related Terms

Research

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research Distinct fibroblast lineages determine dermal architecture in skin development and repair

1235 citations , December 2013 in “Nature”

This study found that skin fibroblasts in mice arise from two distinct lineages which contribute differently to dermal structure and repair, impacting hair follicle formation during wound healing.

research Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis

338 citations , July 2009 in “Development”

This study demonstrates that Sox2-positive dermal papilla cells specify particular hair follicle types by showing heterogeneity in gene expression and pathway activation in these cells.

research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells

330 citations , December 2009 in “Cell stem cell”

This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.

research Review of hair follicle dermal cells

321 citations , December 2009 in “Journal of Dermatological Science”

This review discusses the role of dermal cells in hair follicle regeneration and morphogenesis and highlights their potential therapeutic implications, but it reports no new empirical findings.

Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair

research β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair

314 citations , April 2010 in “Developmental Cell”

This study found that in mice, inactivating beta-catenin in the dermal papilla reduces hair follicle progenitor proliferation and disrupts the hair cycle.

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Community Join

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community Dermal incision with verteporfin

4 upvotes 10 months ago

Dermal incision with verteporfin is being explored as a potential hair loss treatment by dermatologist Melissa Toyos, with promising before-and-after photos shared on social media. The conversation discusses its potential effectiveness compared to other treatments like Minoxidil, Finasteride, and RU58841.

community Conversation with 3-4 top dermatologists - no consensus

5 upvotes 4 months ago

Dermatologists have differing opinions on hair loss treatments, with some using topical dutasteride, oral minoxidil, exosome therapy, PRP, and various other therapies. The user plans to use a topical solution of dutasteride, minoxidil, tretinoin, PRP, and LLLT.

community Dermastamp microneedling: needle length, frequency, and timing minoxidil after?

in Microneedling 7 upvotes 5 months ago

The conversation discusses using a dermastamp for microneedling to treat hair loss, focusing on needle length and frequency. Users share their routines, including applying minoxidil after microneedling, with some waiting 24 hours to avoid side effects.

community A flowchart showing how dermatologists treat male-pattern baldness from UpToDate, the industry-standard reference

in Treatment 12 upvotes 5 months ago

Dermatologists use treatments like oral minoxidil, finasteride, and RU58841 for male-pattern baldness, considering side effects and patient preferences. Photobiomodulation is noted as mildly effective but costly, while PRP is debated for its effectiveness compared to microneedling.

community Dermaroll and topical min/fin for 4 months now. Does this look like the start of something?

in Is this regrowth? 13 upvotes 5 months ago

A 44-year-old is using dermarolling, topical minoxidil, and finasteride for hairline concerns, noticing fine hairs after 4 months. Others believe his hairline is already excellent for his age.

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