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    Glossary Dermal

    layer beneath the epidermis containing blood vessels and hair follicles

    The term "dermal" refers to anything related to the dermis, which is the thick layer of living tissue below the outer epidermis of the skin. The dermis contains blood vessels, hair follicles, sweat glands, and connective tissue, playing a crucial role in skin health, sensation, and thermoregulation.

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    1. Distinct fibroblast lineages determine dermal architecture in skin development and repair Nature · 2013 · 1235 citations
    2. Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis Development · 2009 · 338 citations
    3. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009 · 330 citations
    4. Review of hair follicle dermal cells Journal of Dermatological Science · 2009 · 321 citations
    5. β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010 · 314 citations
    6. Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages Experimental Dermatology · 2003 · 268 citations
    7. Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth Proceedings of the National Academy of Sciences of the United States of America · 2013 · 256 citations
    8. Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding Nature Medicine · 2013 · 237 citations
    9. Differences in Hair Follicle Dermal Papilla Volume are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999 · 231 citations
    10. Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp Journal of Endocrinology · 1998 · 227 citations
    11. Defining dermal adipose tissue Experimental Dermatology · 2014 · 218 citations
    12. Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular decline Development · 2013 · 211 citations
    13. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003 · 208 citations
    14. Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation Development · 2012 · 207 citations
    15. Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair EMBO journal · 1999 · 204 citations
    16. Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells British Journal of Dermatology · 1998 · 192 citations
    17. Androgen‐inducible TGF‐β1 from balding dermal papilla cells inhibits epithelial cell growth: a clue to understanding paradoxical effects of androgen on human hair growth ˜The œFASEB journal · 2002 · 190 citations
    18. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014 · 184 citations
    19. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995 · 173 citations
    20. Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes Journal of Investigative Dermatology · 2007 · 171 citations
    21. Human dermal stem cells differentiate into functional epidermal melanocytes Journal of Cell Science · 2010 · 164 citations
    22. Liposomal systems as drug delivery vehicles for dermal and transdermal applications Archives of Dermatological Research · 2011 · 151 citations
    23. Comparative Characterization of Hair Follicle Dermal Stem Cells and Bone Marrow Mesenchymal Stem Cells Stem Cells and Development · 2006 · 151 citations
    24. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014 · 149 citations
    25. Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle Journal of Dermatological Science · 2004 · 149 citations
    26. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression Journal of Investigative Dermatology · 2007 · 141 citations
    27. Shh maintains dermal papilla identity and hair morphogenesis via a Noggin–Shh regulatory loop Genes & Development · 2012 · 138 citations
    28. Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice Journal of Clinical Investigation · 2019 · 136 citations
    29. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals Proceedings of the National Academy of Sciences · 2005 · 130 citations
    30. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing Cell stem cell · 2020 · 128 citations