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    Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes

    Sachiko Koyama, Anna Purk, Manpreet Kaur … Anthony L. Mescher

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary In this study, beta-caryophyllene enhanced wound healing in female mice by improving re-epithelialization, cell proliferation, and cell migration, suggesting potential benefits of essential oil compounds in inflammation reduction.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 15

    1. Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer Journal of developmental biology · 2017
    2. Fibroblast Growth Factors: Key Players in Regeneration and Tissue Repair Development · 2017
    3. Macrophages and Fibroblasts During Inflammation and Tissue Repair in Models of Organ Regeneration Regeneration · 2017
    4. Defining Stem Cell Dynamics and Migration During Wound Healing in Mouse Skin Epidermis Nature Communications · 2017
    5. Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin Cold Spring Harbor Perspectives in Medicine · 2014
    6. Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche Nature Reviews Molecular Cell Biology · 2013
    7. Sept4/ARTS Regulates Stem Cell Apoptosis and Skin Regeneration Science · 2013
    8. Characterization of the Human Hair Keratin-Associated Protein 2 (KRTAP2) Gene Family Journal of Investigative Dermatology · 2012
    9. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011
    10. Molecular Evolution of the Keratin Associated Protein Gene Family in Mammals: Role in the Evolution of Mammalian Hair BMC Evolutionary Biology · 2008
    11. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    12. Hydrogen Peroxide Disrupts Scarless Fetal Wound Repair Wound Repair and Regeneration · 2005
    13. Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone Journal of Investigative Dermatology · 2005
    14. Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2002
    15. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002