Fibroblast Growth Factors: Key Players in Regeneration and Tissue Repair

    November 2017 in “ Development ”
    Luigi Maddaluno, Corinne Urwyler, Sabine Werner
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    TLDR Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
    The document from November 14, 2017, discussed the role of Fibroblast Growth Factors (FGFs) in tissue repair and regeneration. FGFs were found to control the migration, proliferation, differentiation, and survival of different cell types, and influence the expression of other factors involved in the regenerative response. The document highlighted the importance of understanding FGF activities for appropriate modulation of FGF signaling after injury to prevent impaired healing and promote organ regeneration in humans. FGFs were found to be crucial in various biological processes, including wound healing, bone repair, muscle differentiation, and liver regeneration. In the context of hair growth, FGF9 from dermal gamma delta T cells induced hair follicle neogenesis after wounding. However, the document did not provide specific numbers of participants in the studies, limiting the strength of the conclusions.
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