Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration
June 2016
in “
PloS one
”
TLDR Zebrafish need MYC and FGF to regenerate inner ear hair cells.
The study concluded that Myc and Fgf signaling pathways were essential for the regeneration of neuromast hair cells in zebrafish. Blocking these pathways significantly reduced hair cell regeneration, indicating their critical roles in the proliferation and differentiation of hair cell progenitors. The findings provided insights into the molecular mechanisms of hair cell regeneration, suggesting potential therapeutic targets for treating hearing loss and balance disorders in humans.