Topical and Nutricosmetic Products for Healthy Hair and Dermal Anti-Aging Using Dual-Acting Plant-Based Peptides, Hormones, and Cannabinoids

    May 2021 in “ FASEB bioAdvances ”
    Nicholas J. Sadgrove, Monique S. J. Simmonds
    TLDR Plant-based products can improve hair and skin health without harmful side effects.
    The review explores the potential of plant-based peptides, hormones, and cannabinoids in topical and nutricosmetic products for promoting healthy hair and dermal anti-aging. It highlights the adverse effects of retinoids on hair health and suggests plant-based alternatives like cytokinins, phytoestrogens, and cannabinoids, which can promote collagen synthesis and hair growth without negative side effects. The document emphasizes the dual-acting properties of these compounds, which can address both hair growth and skin aging. Key findings include the efficacy of lysine and arginine-rich peptides, the role of CB2 receptor-specific cannabinoids in lipogenesis and wound healing, and the potential of phytoestrogens in modulating estrogen receptors. The review calls for further research to explore these therapies, particularly in male subjects, to better understand their mechanisms and efficacy.
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