The Effect of Tripeptide-Copper Complex on Human Hair Growth In Vitro

    July 2007 in “ Archives of Pharmacal Research ”
    Hyun Keol Pyo, Hyeon Gyeong Yoo, Chong Hyun Won, Seung Ho Lee, Yong‐Kook Kang, Hee Chul Eun, Kwang Hyun Cho, Kyu Han Kim
    Image of study
    TLDR A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.
    The study from 2007 found that a tripeptide-copper complex, AHK-Cu, stimulated the elongation of human hair follicles and the proliferation of dermal papilla cells (DPCs) at concentrations between 10^-12 and 10^-9 M. The research involved 240 hair follicles from three volunteers and showed that while AHK-Cu at 10^-9 M did not significantly reduce the number of apoptotic DPCs, it did increase the Bcl-2/Bax ratio and decreased levels of apoptosis markers caspase-3 and PARP. These findings suggest that AHK-Cu may promote hair growth by stimulating DPC proliferation and preventing apoptosis, indicating its potential as a therapeutic agent for hair growth promotion.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 34 results

      community Alternatives to Minox for pet safety

      in Minoxidil  2 upvotes 2 weeks ago
      The conversation discusses alternatives to minoxidil for beard growth, focusing on a product called Neofollics Beard Growth Serum, which claims to be effective without using minoxidil. Concerns are raised about its ingredients and effectiveness, especially considering pet safety.

      community Looking for recommendations for a Copper Tripeptide-1 solution

      in Product  3 upvotes 1 year ago
      The conversation is about recommendations for Copper Tripeptide-1 solutions to enhance hair loss treatment, with a focus on using Reviv Hair Serum alongside LLLT therapy. The user also discusses using Minoxidil, RU58841, and other compounds to manage hair shedding and improve hair thickness.

      community IGF-1 and Peptides? Miracle molecule waiting to be found

      in Research/Science  10 upvotes 4 months ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community Anyone tried Thicair? thoughts?

      in Product 5 months ago
      Thicair is a product combining microneedling and subdural vitamins for hair loss, containing ingredients like Panax Ginseng Root Extract and Copper Tripeptide-1. Users are skeptical, with one calling it "quackery."

    Related Research

    7 / 7 results