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    Glossary TRPV3

    protein channel involved in skin and hair follicle function

    TRPV3 is a protein that functions as an ion channel in the cell membranes of skin and hair follicle cells. It plays a crucial role in sensing temperature and chemical stimuli, and its proper function is essential for maintaining healthy skin and hair growth. Mutations in the TRPV3 gene can lead to skin disorders and hair loss conditions, making it a significant focus in dermatological and trichological research.

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    Research 10 of 496

    1. TRPV3 as a Therapeutic Target for Itch Journal of Investigative Dermatology · 2012 · 88 citations
    2. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017 · 77 citations
    3. Influence of TRPV3 mutation on hair growth cycle in mice Biochemical and Biophysical Research Communications · 2007 · 59 citations
    4. Olmsted Syndrome Caused by a Homozygous Recessive Mutation in TRPV3 Journal of Investigative Dermatology · 2014 · 56 citations
    5. Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole EMBO reports · 2021 · 28 citations
    6. Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses Journal of Investigative Dermatology · 2018 · 26 citations
    7. TRPV4 Is Expressed in Human Hair Follicles and Inhibits Hair Growth In Vitro Journal of Investigative Dermatology · 2018 · 25 citations
    8. Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol Journal of Biological Chemistry · 2022 · 24 citations
    9. Mechanisms of proton inhibition and sensitization of the cation channel TRPV3 The Journal of General Physiology · 2020 · 15 citations
    10. TRPV Channels in Osteoarthritis: A Comprehensive Review Biomolecules · 2024 · 14 citations
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