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    Glossary TRPV4

    protein channel regulating calcium flow in cells

    TRPV4 is a type of protein found in the cell membranes that acts as an ion channel, allowing calcium and other ions to pass into the cell. It plays a crucial role in various physiological processes, including the regulation of skin barrier function, hair growth, and response to mechanical and osmotic stress. Dysfunction in TRPV4 can be linked to certain skin and hair disorders, as well as other medical conditions.

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    Research 10 of 393

    1. Localization of mechanosensitive channel TRPV4 in mouse skin Neuroscience Letters · 2003 · 123 citations
    2. TRPV3 as a Therapeutic Target for Itch Journal of Investigative Dermatology · 2012 · 88 citations
    3. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017 · 77 citations
    4. Influence of TRPV3 mutation on hair growth cycle in mice Biochemical and Biophysical Research Communications · 2007 · 59 citations
    5. Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole EMBO reports · 2021 · 28 citations
    6. Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses Journal of Investigative Dermatology · 2018 · 26 citations
    7. TRPV4 Is Expressed in Human Hair Follicles and Inhibits Hair Growth In Vitro Journal of Investigative Dermatology · 2018 · 25 citations
    8. Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol Journal of Biological Chemistry · 2022 · 24 citations
    9. Mechanisms of proton inhibition and sensitization of the cation channel TRPV3 The Journal of General Physiology · 2020 · 15 citations
    10. TRPV Channels in Osteoarthritis: A Comprehensive Review Biomolecules · 2024 · 14 citations
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