Treatment Advances for Acne Vulgaris: The Scientific Role of Cannabinoids

CBD may increase hair counts slightly, but results are minimal without additional treatments like minoxidil or finasteride. Some users suggest combining CBD with other methods for better results.

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

Finasteride effectively treated hormonal acne for multiple users, including the original poster. Topical treatments like Winlevi are effective but expensive and not always covered by insurance.

A user discusses a novel hemp extract for hair regrowth, which showed superior results to finasteride and minoxidil. The formula includes CBD, CBDV, THCV, delta 9 THC, cannabigerol, and cannabinol, combined with menthol, peppermint oil, ethanol, Emu oil, HFA 134A propellant, and dimethicone.

Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.