Teratogenic Effect of Isotretinoin in Both Fertile Females and Males: A Review

    March 2021 in “ Experimental and Therapeutic Medicine ”
    Carmen‐Cristina Draghici, Raluca‐Gabriela Miulescu, Răzvan Petca … Florica Șandru
    Studysummary This review examines recent literature on isotretinoin's teratogenic effects in both fertile females and males, analyzing its role in causing congenital malformations but provides no new clinical results.
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    Research cited in this study 2

    1. Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity Acta dermato-venereologica · 2017
    2. Skin Expression of Mammalian Target of Rapamycin and Forkhead Box Transcription Factor O1, and Serum Insulin-Like Growth Factor-1 in Patients with Acne Vulgaris and Their Relationship with Diet British Journal of Dermatology · 2016