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GlossaryBirth Defects (Congenital Defects)

structural or functional abnormalities present at birth

Birth defects, also known as congenital disorders or congenital anomalies, are structural or functional abnormalities that occur during intrauterine development. These defects can affect various parts of the body, including the heart, brain, or limbs, and can result from genetic factors, environmental exposures, or a combination of both. They can range from minor issues that may not require treatment to severe conditions that can significantly impact a person's quality of life or even be life-threatening.

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research Genetic Characterization of Congenital Defects in Dogs: Caudal Dysplasia, Ectodermal Dysplasia, and Mucopolysaccharidosis VII

September 2013 in “Helda (University of Helsinki)”

Mutations in specific genes cause certain congenital defects in dogs, aiding in understanding similar human diseases.

research Teratogenic Effect of Isotretinoin in Both Fertile Females and Males: A Review

19 citations , March 2021 in “Experimental and Therapeutic Medicine”

Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.

research Adverse Reactions to Oral Retinoids: An Update

53 citations , October 1993 in “Drug Safety”

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

research Secondary Cicatricial and Other Permanent Alopecias

20 citations , July 2008 in “Dermatologic Therapy”

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

research Chemical Danger in Hair Keratin Care

January 2023

Hair keratin treatments can be harmful, potentially causing health issues like skin reactions and cancer.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Male (24) Using Dutasteride Since 2020 – Concerns About Having Kids

in Finasteride/Dutasteride 90 upvotes 10 months ago

A 24-year-old male using dutasteride for hair loss is worried about its effects on fertility and future children's health. Users advise consulting a doctor, possibly switching to finasteride, or stopping dutasteride before conception due to its impact on sperm count.

community Stopping Dutasteride to have a baby

in Finasteride/Dutasteride 70 upvotes 1 year ago

A user plans to stop Dutasteride to conceive a child, seeking advice on hair maintenance. Suggestions include switching to Finasteride, but many emphasize prioritizing child safety.

community I was on 2.5 mg oral minoxidil

in Progress Pictures 468 upvotes 1 year ago

User took 2.5 mg oral minoxidil, saw hair growth but stopped due to excessive body hair. Recently started finasteride and plans to update progress.

community Hair loss research is a money grab

in Chat 217 upvotes 2 weeks ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

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