Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function

    September 2016 in “ Reviews in Endocrine and Metabolic Disorders ”
    Christos C. Zouboulis, Mauro Picardo, Jun Qiang … Marlon R. Schneider
    Studysummary This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 31

    1. Sebaceous Lipids Are Essential for Water Repulsion, Protection Against UVB-Induced Apoptosis, and Ocular Integrity in Mice Development · 2016
    2. Expression of Dermcidin in Sebocytes Supports a Role for Sebum in the Constitutive Innate Defense of Human Skin Journal of Dermatological Science · 2015
    3. Sebocytes Differentially Express and Secrete Adipokines Experimental Dermatology · 2015
    4. Acne-Associated Syndromes: Models for Better Understanding of Acne Pathogenesis Journal of The European Academy of Dermatology and Venereology · 2010
    5. Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli Mediators of Inflammation · 2010
    6. Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating Beta-Defensin-2 Expression Journal of Investigative Dermatology · 2009
    7. Epigen Transgenic Mice Develop Enlarged Sebaceous Glands Journal of Investigative Dermatology · 2009
    8. Role of FGFR2-Signaling in the Pathogenesis of Acne Dermato-endocrinology · 2009
    9. Hormones and the Pilosebaceous Unit Dermato-endocrinology · 2009
    10. Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2009
    11. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    12. Human Skin Stem Cells and the Aging Process Experimental gerontology · 2008
    13. Hedgehog Signaling, Keratin 6 Induction, And Sebaceous Gland Morphogenesis American Journal Of Pathology · 2008
    14. More Than One Way to Skin Genes & Development · 2008
    15. Phylogeny of the Hair Follicle: The Sebogenic Hypothesis Journal of Investigative Dermatology · 2007
    16. The Role of Fibroblast Growth Factor Receptor 2b in Skin Homeostasis and Cancer Development The EMBO Journal · 2007
    17. Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes Hormone and metabolic research · 2007
    18. Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development Developmental Cell · 2006
    19. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    20. The Human Skin as a Hormone Target and an Endocrine Gland Hormones · 2004
    21. Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis Development · 2003
    22. Human Skin Is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1) Journal of Investigative Dermatology · 2003
    23. Corticotropin-Releasing Hormone: An Autocrine Hormone That Promotes Lipogenesis in Human Sebocytes Proceedings of the National Academy of Sciences · 2002
    24. Expression of ΔNLef1 in Mouse Epidermis Results in Differentiation of Hair Follicles into Squamous Epidermal Cysts and Formation of Skin Tumors Development · 2002
    25. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    26. Deregulated Expression of c-Myc Depletes Epidermal Stem Cells Nature Genetics · 2001
    27. Abnormal Differentiation of Epidermis in Transgenic Mice Constitutively Expressing Cyclooxygenase-2 in Skin Proceedings of the National Academy of Sciences · 2001
    28. Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001
    29. C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny Current Biology · 2001
    30. The Human Sebocyte Culture Model Provides New Insights Into Development and Management of Seborrhoea and Acne Dermatology · 1998
    31. Comparative Studies of the Ultrastructure of the Sebaceous Gland Tissue and Cell · 1985

    Related research 2

    1. Culture of the Human Pilosebaceous Unit, Hair Follicle, and Sebaceous Gland Experimental Dermatology · 2018
    2. Histological Studies on the Hair Follicle and Skin of Chegu Goat Indian Journal of Small Ruminants (The) · 2012