C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny

April 2001 in “ Current Biology ”

Isabel Arnold, Fiona M. Watt

c-Myc keratinocytes sebaceous gland hair follicle epidermal thickening stem cells sebocyte differentiation neoplastic processes

Studysummary This study found that transient activation of c-Myc in transgenic mice stimulates keratinocyte proliferation and sebocyte differentiation, affecting normal epidermal and hair follicle development.

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