Comparative Studies of the Ultrastructure of the Sebaceous Gland
January 1985
in “
Tissue and Cell
”
TLDR Sebum production in sebaceous glands is similar to hair growth, involving cell development and degeneration.
The study from 1985 investigated the ultrastructure of sebaceous glands in humans and domestic animals, revealing that sebum production involved a process similar to hair growth. Sebum was produced from a column of developing and degenerating cell populations originating from peripheral progenitor cells at the base of the gland's lobe. The peripheral cells near the gland's neck contributed keratin to the secretory product, but did not directly participate in sebocyte production. The research highlighted the differentiation and lipid accumulation in sebocytes, leading to cell degeneration and sebum release.
