Androgenic Hormone Profile of Adult Women with Acne

    January 2013 in “ Dermatology
    Marisa Gonzaga da Cunha, Fernando Luiz Affonso Fonseca, Carlos D Aparecida Santos Machado
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    TLDR Over half of the adult women with acne in the study had higher than normal levels of male hormones, especially DHEA.
    The study analyzed the androgenic hormone levels in 835 adult female patients with acne and found that 54.56% exhibited hyperandrogenism, with dehydroepiandrosterone (DHEA) being the most frequently elevated hormone. The average age of participants was 26.64 years, and most had Grade II facial acne. The study also reported that 56.52% of the patients had altered androgen levels, with 39.64% showing increased DHEA levels and 21.31% having increased androstenedione levels. Total testosterone was elevated in 10.77% of the patients. These findings highlight the need for comprehensive hormone profiling, including DHEA-S, testosterone, DHT, DHEA, and androstenedione, in the clinical management of adult female acne to detect hyperandrogenic states and manage potential relapses.
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