Polycystic Ovary Syndrome in Adolescents

    July 2012 in “ Current Opinion in Obstetrics & Gynecology ”
    Beth W. Rackow
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    TLDR Early diagnosis and treatment are key to managing health risks in teens with PCOS.
    The document from 2012 reviews the challenges of diagnosing and treating polycystic ovary syndrome (PCOS) in adolescents. It emphasizes the controversy surrounding the diagnostic criteria, with a growing consensus towards using the Rotterdam criteria to prevent overdiagnosis. Adolescents with PCOS are noted to have a higher prevalence of metabolic syndrome (26-35%) and sleep disorders, such as obstructive sleep apnea (OSA) and excessive daytime sleepiness (EDS), compared to matched controls. Lifestyle modification is the primary treatment recommended, with weight management being crucial for improving menstrual function and reducing cardiovascular risks. The use of insulin sensitizers like metformin is common, showing benefits in adolescents with PCOS, but further research is needed to confirm its long-term effectiveness. The document concludes that early diagnosis and intervention are essential to mitigate the long-term health risks associated with PCOS and its metabolic comorbidities in adolescents.
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