Metabolic Syndrome: A New Definition and Management Guidelines

    December 2022 in “ Arterial Hypertension ”
    Piotr Dobrowolski, Aleksander Prejbisz, Alina Kuryłowicz, Alicja Baska, Paweł Burchardt, Krzysztof Chlebus, Grzegorz Dzida, Piotr Jankowski, Jerzy Jaroszewicz, Paweł Jaworski, Karol Kamiński, Agnieszka Kapłon‐Cieślicka, Marek Klocek, Michał Kukla, Artur Mamcarz, Agnieszka Mastalerz–Migas, Krzysztof Narkiewicz, Lucyna Ostrowska, Daniel Śliż, Wiesław Tarnowski, Jacek Wolf, Mariusz Wyleżoł, Tomasz Zdrojewski, Maciej Banach, Andrzej Januszewicz, Paweł Bogdański
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    TLDR New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.
    The document presents new guidelines for defining and managing metabolic syndrome (MetS), highlighting its role as a cluster of modifiable cardiovascular risk factors, including obesity, hypertension, and disordered carbohydrate and lipid metabolism. It emphasizes the importance of early diagnosis and intervention, with management strategies focusing on lifestyle modifications such as dietary changes, increased physical activity, and smoking cessation, alongside medical treatments like GLP-1 receptor agonists and metformin for specific patient groups. The guidelines also address the management of associated conditions like type 2 diabetes, dyslipidemia, and hypertension, recommending a multidisciplinary approach to prevent cardiovascular and organ complications. The document underscores the significance of weight loss for nephroprotection and the treatment of metabolic-associated fatty liver disease (MAFLD), which affects 25% of the global population. Overall, the guidelines stress comprehensive management to address the complex pathogenesis of MetS.
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