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    Glossary Androstenedione

    steroid hormone precursor to testosterone and estrogen

    Androstenedione, often referred to as Andro, is a steroid hormone that serves as a precursor in the biosynthesis of testosterone and estrogen. It is produced in the adrenal glands, ovaries, and testes, and plays a crucial role in the development of secondary sexual characteristics and reproductive function. Elevated levels of androstenedione can be associated with conditions like polycystic ovary syndrome (PCOS) and certain forms of adrenal hyperplasia.

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    1. Puberty in Boys: Correlation of Plasma Levels of Gonadotropins (LH, FSH), Androgens (Testosterone, Androstenedione, Dehydroepiandrosterone and Its Sulfate), Estrogens (Estrone and Estradiol) and Progestins (Progesterone and 17-Hydroxyprogesterone) The Journal of Clinical Endocrinology & Metabolism · 1975 · 96 citations
    2. Elevated serum androstenedione is associated with a more severe phenotype in women with polycystic ovary syndrome (PCOS) Hormones · 2014 · 28 citations
    3. The influence of obesity on Androstenedione to Testosterone ratio in women with polycystic ovary syndrome (PCOS) and hyperandrogenemia Gynecological Endocrinology · 2011 · 15 citations
    4. Scalp hair 17‐hydroxyprogesterone and androstenedione as a long‐term therapy monitoring tool in congenital adrenal hyperplasia Clinical Endocrinology · 2016 · 9 citations
    5. Androstenedione Strength and Conditioning Journal · 1999
    6. A Model for Predicting Polycystic Ovary Syndrome Using Serum AMH, Menstrual Cycle Length, Body Mass Index and Serum Androstenedione in Chinese Reproductive Aged Population: A Retrospective Cohort Study Frontiers in Endocrinology · 2022 · 5 citations
    7. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    8. Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with the polycystic ovary syndrome. Journal of Clinical Investigation · 1989 · 202 citations
    9. Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin 2001 · 196 citations
    10. SERUM STEROIDS AND PITUITARY HORMONES IN FEMALE PUBERTY: A PARTLY LONGITUDINAL STUDY Clinical Endocrinology · 1980 · 186 citations
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