Maternal PPARγ Protects Nursing Neonates by Suppressing the Production of Inflammatory Milk

    July 2007 in “ Genes & Development ”
    Yihong Wan, Alan Saghatelian, Ling Wa Chong … Ronald M. Evans
    Studysummary This study found that maternal PPARγ is essential for preventing the production of inflammatory lipids in mouse milk, which can otherwise cause inflammation, alopecia, and growth retardation in nursing pups.
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    Research cited in this study 4

    1. Expression of Cyclooxygenase Isozymes During Morphogenesis and Cycling of Pelage Hair Follicles in Mouse Skin: Precocious Onset of the First Catagen Phase and Alopecia Upon Cyclooxygenase-2 Overexpression Journal of Investigative Dermatology · 2003
    2. Cyclooxygenase-2 Overexpression in the Skin of Transgenic Mice Results in Suppression of Tumor Development PubMed · 2002
    3. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables Experimental dermatology · 2001
    4. The Biology of Hair Follicles The New England Journal of Medicine · 1999