Role of Insulin, Insulin-Like Growth Factor-1, Hyperglycemic Food, and Milk Consumption in the Pathogenesis of Acne Vulgaris

    August 2009 in “ Experimental dermatology ”
    Bodo C. Melnik, Gerd Schmitz
    Studysummary This article reviews the role of IGF-1 in acne pathogenesis and discusses how diet and smoking may influence insulin/IGF-1 signaling, but reports no new clinical results.
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    Research cited in this study 6

    1. Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2009
    2. Impact of Metformin and Rosiglitazone Treatment on Glucose Transporter 4 mRNA Expression in Women with Polycystic Ovary Syndrome European journal of endocrinology · 2008
    3. Metformin Improves Polycystic Ovary Syndrome Symptoms Irrespective of Pre-Treatment Insulin Resistance European journal of endocrinology · 2007
    4. Polycystic Ovary Syndrome: Comprehensive Overview and Diagnostic Criteria The Lancet · 2007
    5. The Human Skin as a Hormone Target and an Endocrine Gland Hormones · 2004
    6. Regulation of Human Dermal Papilla Cell Production of Insulin-Like Growth Factor Binding Protein-3 by Retinoic Acid, Glucocorticoids, and Insulin-Like Growth Factor-1 Journal of cellular physiology · 1996