Compendium of Polycystic Ovarian Syndrome and Its Relevance in Glycation and Diabetes

    January 2022 in “ Journal of experimental and clinical medicine ”
    Payal Poojari, Amruta PADGAONKAR, Additiya Paramanya, Ahmad H. Ali
    Image of study
    TLDR PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
    Polycystic Ovarian Syndrome (PCOS) is closely linked with metabolic disorders such as Type 2 Diabetes Mellitus (T2DM), with insulin resistance (IR) being a central factor. The review highlights the connection between PCOS, IR, and the formation of advanced glycation end products (AGEs), which contribute to IR and can worsen PCOS and diabetes symptoms. It suggests that targeting the interaction between AGEs and their receptors (RAGE) may help in managing IR-related complications. The document also discusses the potential benefits of M. oleifera and S. platensis in providing symptomatic relief for PCOS and mentions common medications like metformin, inositol, thiazolidinediones, and spironolactone used for treatment. The review underscores the complex relationship between hormonal imbalances and metabolic dysfunctions in PCOS.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 12 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  53 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community My scalp punch biopsy results🤔?

      in Female  9 upvotes 1 year ago
      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

      community Bryan Johnson just dropped his anti hair loss formula

      in Treatment  339 upvotes 10 months ago
      Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

      community having hair loss as a teen SUCKS. A LOT.

      in Female  12 upvotes 2 years ago
      A teenage girl who has been diagnosed with ADA and is struggling with hair loss, which has caused her to lose confidence. She is looking for recommendations on treatments such as finasteride or Minoxidil, and lifestyle advice including vitamins and other supplements that might help with the issue.

    Similar Research

    6 / 1000+ results