Compendium of Polycystic Ovarian Syndrome and Its Relevance in Glycation and Diabetes

January 2022 in “ Journal of experimental and clinical medicine ”

Payal Poojari, Amruta PADGAONKAR, Additiya Paramanya, Ahmad H. Ali

Polycystic Ovarian Syndrome Type 2 Diabetes Mellitus insulin resistance advanced glycation end products receptors for advanced glycation end products M. oleifera S. platensis metformin inositol thiazolidinediones spironolactone hormonal imbalances metabolic dysfunctions PCOS T2DM IR AGEs RAGE moringa spirulina

Studysummary This review examines the relationship between glycation, insulin resistance, and PCOS, discussing various treatments and highlighting M. oleifera and S. platensis as potential therapeutic agents, but reports no new clinical results.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

Read the full study on doi.org →

Discuss this study in the Community →

Similar research 5

Women With Polycystic Ovary Syndrome: A Review of Susceptibility to Type 2 Diabetes Cureus · 2023
Insulin Resistance and Polycystic Ovary Syndrome John Wiley & Sons, Ltd eBooks · 2004
Ethnicity, Obesity, and the Prevalence of Impaired Glucose Tolerance and Type 2 Diabetes in PCOS: A Systematic Review and Meta-Regression Human Reproduction Update · 2018
Polycystic Ovary Syndrome: Diagnosis, Symptoms, and Management Practical diabetes · 2005
The Frequency of Polycystic Ovary Syndrome in Women With Prediabetes Compared With Normoglycemic Women Frontiers in Endocrinology · 2025

Related Community Posts Join

6 / 1000+ results

community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.

15 upvotes 8 years ago

Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.

community Positive Hair Result in Patient using Tirzepatide

4 upvotes 1 year ago

A 57-year-old man with male pattern hair loss and insulin resistance experienced hair regrowth and weight loss after using tirzepatide, without other hair treatments. Dysregulated glucose metabolism is linked to hair loss, with tirzepatide potentially improving hair density by normalizing insulin resistance.

community Sugar and Hair loss connections

in Research/Science 41 upvotes 1 year ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

community Anyone with high glucose, insulin resistance, pre-diabetes or diabetes notice any regrowth after starting treatment?

5 upvotes 1 year ago

A 21-year-old male with advanced hair loss (NW7) started using finasteride and minoxidil 10 months ago but hasn't seen much progress. He is pre-diabetic with stage 1 hypertension and is seeking insights on whether treating these conditions could improve hair regrowth.

community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

55 upvotes 2 years ago

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.