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Glossary Metabolic Dysfunction

abnormalities in body's metabolic processes affecting energy conversion

Metabolic dysfunction refers to abnormalities in the body's metabolic processes, which can lead to issues like insulin resistance, obesity, and abnormal lipid levels. These disruptions can affect how the body converts food into energy and how it manages essential functions, potentially contributing to conditions such as type 2 diabetes and cardiovascular disease.

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Research

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Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction

44 citations , May 2012 in “Endocrinology”

This review discusses the etiology of polycystic ovary syndrome, emphasizing the role of genetic and environmental factors, and reports no new experimental findings.

research Metabolic dysfunction in obese Hispanic women with polycystic ovary syndrome

13 citations , April 2015 in “Human Reproduction”

Obese Hispanic women with PCOS are at higher risk for metabolic problems than non-Hispanic white women.

research Metabolic dysfunction in female mice with disruption of 5α-reductase 1

11 citations , January 2017 in “Journal of Endocrinology/Journal of endocrinology”

This study observed that female mice with disrupted 5α-reductase 1 showed increased insulin resistance and hepatic steatosis, suggesting altered glucocorticoid metabolism contributes to metabolic disorders.

research Cutaneous Clues to Metabolic Dysfunction: Dermatological Manifestations of Diabetes and Insulin Resistance in Clinical Practice

March 2026 in “Current Research in Diabetes & Obesity Journal”

This abstract introduces the "Current Research in Diabetes & Obesity Journal" as an international, peer-reviewed, Open Access journal dedicated to enhancing knowledge, fostering research, and promoting improved treatments for individuals with diabetes and obesity, but does not report specific study results.

Metabolic Dysfunction-Associated Steatotic Liver Disease Is Associated With Androgenetic Alopecia in Adults With Stronger Effects in Women and Unhealthy Lifestyles

research Metabolic dysfunction-associated steatotic liver disease is associated with androgenetic alopecia in adults with stronger effects in women and unhealthy lifestyles

November 2025 in “Scientific Reports”

This study found that metabolic dysfunction-associated steatotic liver disease is linked to a higher risk of androgenetic alopecia, especially in women and individuals with certain lifestyle patterns.

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Community Join

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community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community What can be the real reason of Finasteride SE ?

18 upvotes 1 year ago

Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.

community 5mg cialis daily to deal with dutasteride

in Finasteride/Dutasteride 71 upvotes 8 months ago

Cialis is used to manage erectile dysfunction caused by finasteride and dutasteride, with mixed results. Some users report improvement, while others consider stopping the medication due to side effects.

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learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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