Search
for

    Glossary Mitochondrial Dysfunction

    cells' energy production is impaired due to faulty mitochondria

    Mitochondrial dysfunction refers to a condition where the mitochondria, the energy-producing structures within cells, fail to work correctly. This can lead to reduced energy production, increased oxidative stress, and can contribute to various diseases, including neurodegenerative disorders and metabolic syndromes. For professionals, it is often associated with mutations in mitochondrial DNA or nuclear genes that affect mitochondrial function.

    Related Terms

    Research 10 of 1000+

    1. Mitochondrial dysfunction as a cause of ageing Journal of Internal Medicine · 2008 · 384 citations
    2. Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review Antioxidants · 2018 · 280 citations
    3. Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients Molecular psychiatry · 2013 · 198 citations
    4. Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront Androgens · 2021 · 9 citations
    5. Environmental Pollution, Oxidative Stress and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis and Aging. 2020 · 6 citations
    6. Mitochondrial dysfunction in diabetic neuropathy may be involved in the development of neuropathic pain via a reduction in neurosteroid synthesis F1000Research · 2017 · 4 citations
    7. Mitochondrial dysfunction in an animal model of diabetic neuropathy is associated with a reduction of neurosteroid synthesis. F1000Research · 2018 · 1 citations
    8. Author response: Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression 2017 · 1 citations
    9. Secreted Frizzled‐Related Protein 2 ( SFRP2 ) Induces Follistatin‐Like 1 ( FSTL1 ) to Regulate Dihydrotestosterone ( DHT )‐Induced Dermal Papilla Cell Mitochondrial Dysfunction and Senescence Aging Cell · 2026
    10. ACOD1 deficiency promotes DDX1 methylation–mediated mitochondrial dysfunction and dermal papilla cell senescence in androgenetic alopecia BMC Medicine · 2026
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →