Search
for

    Glossary Mitochondrial Dysfunction

    cells' energy production is impaired due to faulty mitochondria

    Mitochondrial dysfunction refers to a condition where the mitochondria, the energy-producing structures within cells, fail to work correctly. This can lead to reduced energy production, increased oxidative stress, and can contribute to various diseases, including neurodegenerative disorders and metabolic syndromes. For professionals, it is often associated with mutations in mitochondrial DNA or nuclear genes that affect mitochondrial function.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Mitochondrial dysfunction as a cause of ageing Journal of Internal Medicine · 2008 · 384 citations
    2. Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review Antioxidants · 2018 · 280 citations
    3. Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients Molecular psychiatry · 2013 · 198 citations
    4. Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront Androgens · 2021 · 9 citations
    5. Environmental Pollution, Oxidative Stress and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis and Aging. 2020 · 6 citations
    6. Mitochondrial dysfunction in diabetic neuropathy may be involved in the development of neuropathic pain via a reduction in neurosteroid synthesis F1000Research · 2017 · 4 citations
    7. Mitochondrial dysfunction in an animal model of diabetic neuropathy is associated with a reduction of neurosteroid synthesis. F1000Research · 2018 · 1 citations
    8. Author response: Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression 2017 · 1 citations
    9. Secreted Frizzled‐Related Protein 2 ( SFRP2 ) Induces Follistatin‐Like 1 ( FSTL1 ) to Regulate Dihydrotestosterone ( DHT )‐Induced Dermal Papilla Cell Mitochondrial Dysfunction and Senescence Aging Cell · 2026
    10. ACOD1 deficiency promotes DDX1 methylation–mediated mitochondrial dysfunction and dermal papilla cell senescence in androgenetic alopecia BMC Medicine · 2026
    11. MitoQ upregulates CYP19A1 to protect dermal papilla cells from DHT-induced mitochondrial dysfunction and apoptosis in androgenetic alopecia Biochemical Pharmacology · 2026
    12. 0961 Exploring mitochondrial dysfunction in miniaturized hair follicles: Insights into androgenetic alopecia Journal of Investigative Dermatology · 2025
    13. Mitochondrial Dysfunction in Lichen Planopilaris with Focus on Oxidative Stress and Metabolic Reprogramming International journal of research studies in biosciences · 2025
    14. Mitochondrial dysfunction in metabolic syndrome and inflammatory skin disease Our Dermatology Online · 2024
    15. Dermatologic Manifestations of Mitochondrial Dysfunction: A Review of the Literature International journal of molecular sciences · 2024
    16. 1431 Skin aging and hair follicle stem cell dysfunction caused by T cells with defective mitochondrial metabolism Journal of Investigative Dermatology · 2023
    17. Data_Sheet_1_Disruption of Hars2 in Cochlear Hair Cells Causes Progressive Mitochondrial Dysfunction and Hearing Loss in Mice.docx OPAL (Open@LaTrobe) (La Trobe University) · 2021
    18. 1368 Does mitochondrial dysfunction drive immune privilege collapse in lichen planopilaris pathogenesis? 2018
    19. Decision letter: Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression 2017
    20. Unveiling Therapeutic Potential of Yoga Mitigating Oxidative Stress and Mitochondrial Dysfunction in PCOS: A Randomized Controlled Trial International Journal of Yoga · 2025 · 4 citations
    21. "Treatment of Epstein-Barr Virus, Chronic Fatigue, Mitochondrial Dysfunction, and Insomnia" Biomedical Journal of Scientific & Technical Research · 2022
    22. Recombinant Filaggrin-2 microneedles reverse androgenetic alopecia by rescuing mitochondrial dysfunction in dermal papilla cells International Journal of Biological Macromolecules · 2026
    23. Antiretroviral nucleoside and nucleotide analogues and mitochondria AIDS · 2004 · 138 citations
    24. Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1 Aging · 2017 · 75 citations
    25. Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function Cell death and disease · 2018 · 74 citations
    26. Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice Free radical biology & medicine · 2014 · 53 citations
    27. PKC downregulation upon rapamycin treatment attenuates mitochondrial disease Nature metabolism · 2020 · 26 citations
    28. Photobiomodulation mitigates DHT-induced apoptosis in dermal papilla cells via mitochondrial rescue and Wnt/TGF-β/BMP signaling modulation Journal of Photochemistry and Photobiology B Biology · 2025 · 1 citations
    29. Endosymbiosis-inspired engineering of mitochondrial-enriched extracellular vesicles supercharges host mitochondria via the autophagy-lysosome pathway 2026
    30. A NIR-responsive PDA@RES core-shell nanoplatform accelerates chronic wound healing by remodeling mitochondrial homeostasis and reversing cellular senescence Nano Research · 2026