PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease

    December 2020 in “ Nature metabolism ”
    Miguel Martín-Pérez, Anthony S. Grillo, Takashi Ito … Judit Villén
    Studysummary Martin-Perez et al. show that rapamycin's beneficial effects in a mouse model of Leigh syndrome are linked to the downregulation of protein kinase C.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on nature.com →
    Discuss this study in the Community →

    Research cited in this study 1

    1. Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization Cell Metabolism · 2014