Environmental Pollution, Oxidative Stress, and Thioretinaco Ozonide: Effects of Glyphosate, Fluoride, and Electromagnetic Fields on Mitochondrial Dysfunction in Carcinogenesis, Atherogenesis, and Aging

The review discussed how environmental pollutants like glyphosate, fluoride, and electromagnetic fields contributed to mitochondrial dysfunction, leading to oxidative stress and various health issues such as cancer, heart disease, and aging-related diseases. These pollutants disrupted the active site for oxidative phosphorylation, causing mitochondrial permeability transition pore opening. Electromagnetic fields, both ionizing and non-ionizing, were linked to numerous adverse health effects, including cancer, cardiac arrhythmias, and hair loss. The study highlighted the role of hyperhomocysteinemia and adenosyl methionine deficiency in atherosclerosis and dementia, suggesting that environmental pollutants could accelerate aging and promote chronic diseases through mitochondrial damage.