Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1

    February 2017 in “ Aging ”
    Irina G. Shabalina, Mikhail Yu. Vyssokikh, N. V. Gibanova … Jan Nedergaard
    Studysummary This study found that treating mtDNA mutator mice with the antioxidant SkQ1 delayed aging traits and extended their lifespan, potentially by alleviating mitochondrial dysfunction caused by reactive oxygen species.
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    Research cited in this study 2

    1. Defects in Mitochondrial DNA Replication and Oxidative Damage in Muscle of mtDNA Mutator Mice Free radical biology & medicine · 2014
    2. The Browning of White Adipose Tissue: Some Burning Issues Cell metabolism · 2014