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    Glossary Mitochondrial Dysfunction

    cells' energy production is impaired due to faulty mitochondria

    Mitochondrial dysfunction refers to a condition where the mitochondria, the energy-producing structures within cells, fail to work correctly. This can lead to reduced energy production, increased oxidative stress, and can contribute to various diseases, including neurodegenerative disorders and metabolic syndromes. For professionals, it is often associated with mutations in mitochondrial DNA or nuclear genes that affect mitochondrial function.

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    1. PP405 mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials