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highly targeted anti-androgen that might have minimal systemic effects
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research Advanced Glycation End-Products Inhibit Mesenchymal-Epidermal Interaction by Up-Regulating Proinflammatory Cytokines in Hair Follicles
AGEs may cause hair loss by increasing inflammation in hair follicles.
research Epidermal Expression of Receptor for Advanced Glycation End Products (RAGE) Is Related to Inflammation and Apoptosis in Human Skin
Skin RAGE levels are linked to inflammation and cell death.
research Method for Chronological Recording of Antigen Appearance in Human Head-Hair Shafts and Its Use for Monitoring Glycation Products in Diabetes
The method can help diagnose and monitor diabetes by analyzing hair.
research Compendium of Polycystic Ovarian Syndrome and Its Relevance in Glycation and Diabetes
PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.
research Antiglycants
Anti-glycation treatments might slow skin aging, but more research is needed.
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5 / 677 resultscommunity Is 2-deoxy-D-ribose (2dDR) good for human hair?
Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).
community Advanced AGA and DUPA at 25. Starting Nuclear Stack: Day 178 (6 months-ish)
A user is treating hair loss with Dutasteride, Minoxidil, RU58841, Derminator 2, Vitamin D, Biotin, and Zinc. After 6 months, there's no significant visual improvement, but the user feels less insecure about Retrograde Alopecia.
community Advanced AGA and DUPA at 25. Starting Nuclear Stack: Day 1
User starts Nuclear Stack treatment for hair loss, including Dutasteride, Minoxidil, RU58841, Derminator 2, and supplements. Seeks advice on storing and dosing RU58841.
community [25M] Advanced Hair Loss - Oral Minoxidil + Topical Finastride
A 25-year-old male is experiencing advanced hair loss and is using topical and oral minoxidil, topical finasteride, and vitamin D3, but has not seen significant regrowth. He is considering switching treatments, including oral dutasteride, topical spironolactone, and possibly a scalp biopsy to better understand his condition.
community If fin/min and advanced treatments don’t work—would you ever consider a hair system? Or just shave it and own it?
If treatments like finasteride, minoxidil, PRP, microneedling, and exosomes fail, opinions differ on using a hair system or shaving. Some choose shaving for simplicity, while others consider hair systems despite maintenance concerns.