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Glossary High-Resolution Mass Spectrometry

advanced technique for precise molecular mass measurement

High-Resolution Mass Spectrometry (HRMS) is an advanced analytical technique used to precisely measure the mass of molecules. It provides highly accurate mass measurements, allowing scientists to identify and characterize complex chemical compounds, including those in biological samples like hair, with great specificity.

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Research

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research (Un)targeted Scanning of Locks of Hair for Drugs of Abuse by Direct Analysis in Real Time–High-Resolution Mass Spectrometry

34 citations , January 2016 in “Analytical Chemistry”

This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.

research Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry

17 citations , August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.

research A quantitative ultra-performance liquid chromatography high-resolution mass spectrometry analysis of steroids from human scalp hair

7 citations , April 2022 in “Journal of pharmaceutical and biomedical analysis”

This study describes a new method using high-resolution mass spectrometry for analyzing multiple steroids in human scalp hair, with newborn hair showing the highest steroid concentrations among examined age groups.

research High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile

2 citations , December 2013 in “Xenobiotica”

This study found that the metabolic profile of finasteride in pigs closely matches that of humans, supporting the use of pigs for studying human drug metabolism.

research High resolution full scan liquid chromatography mass spectrometry comprehensive screening in sports antidoping urine analysis

49 citations , December 2017 in “Journal of pharmaceutical and biomedical analysis”

This study developed and validated a high-resolution mass spectrometry method to screen for prohibited substances and analyze six endogenous steroids in urine according to World Antidoping Agency requirements, demonstrating its effectiveness for antidoping analysis.

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Community Join

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community Microneedling aftercare advice

4 upvotes 4 years ago

Microneedling aftercare involves using saline water instead of sea water, and avoiding hyaluronic acid due to its potential pro-inflammatory effects. Users suggest using jojoba oil as a carrier for essential oils like rosemary and lavender, and combining microneedling with minoxidil for better hair regrowth results.

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Experts

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84
SMP Specialist
Craig Bottomley-High
Studham, England, United Kingdom
13+ yrs

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Craig Bottomley-High