Impact of Metformin and Rosiglitazone Treatment on Glucose Transporter 4 mRNA Expression in Women with Polycystic Ovary Syndrome

    Mojca Jensterle, Andrej Janez, Barbara Mlinar … Marija Pfeifer
    Studysummary In this study, treatment with insulin sensitizers significantly increased adipose tissue GLUT4 mRNA expression and improved insulin resistance, menstrual patterns, and androgen profiles in PCOS patients, with rosiglitazone being more effective than metformin.
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    Research cited in this study 2

    1. Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2003
    2. Polycystic Ovary Syndrome: Clinical and Biochemical Features New England journal of medicine/˜The œNew England journal of medicine · 1995