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GlossaryMetformin (Glucophage)

oral diabetes medication that lowers blood sugar levels

Metformin, also known by brand names such as Glucophage, is an oral medication commonly used to manage type 2 diabetes. It works by reducing glucose production in the liver and improving the body's sensitivity to insulin, thereby helping to control blood sugar levels. Additionally, metformin is sometimes used off-label for conditions like polycystic ovary syndrome (PCOS) due to its effects on insulin resistance.

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learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline

1265 citations, October 2013 in “The Journal of Clinical Endocrinology and Metabolism”

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

research Polycystic Ovary Syndrome: Comprehensive Overview and Diagnostic Criteria

989 citations, August 2007 in “The Lancet”

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

research Epidemiology, Diagnosis, and Management of Polycystic Ovary Syndrome

951 citations, December 2013 in “Clinical epidemiology”

PCOS is a common hormonal disorder in women that can be managed with lifestyle changes and various medications.

Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

research Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

926 citations, June 2010 in “BMC Medicine”

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review

343 citations, December 2008 in “Endocrine Reviews”

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

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community C’est terrible - at my wits end

in Female 443 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.