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Glossary Lipid Metabolism

processes by which the body breaks down and utilizes fats

Lipid metabolism, also known as fat metabolism, refers to the processes by which the body breaks down and utilizes fats for energy, as well as the synthesis and storage of fats. This involves the digestion of dietary fats, the transport of lipids through the bloodstream, and the conversion of fats into energy or storage molecules like triglycerides. Key pathways include beta-oxidation, where fatty acids are broken down in the mitochondria, and lipogenesis, where new fats are synthesized.

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Research

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research The Lipid Profiles in Different Characteristics of Women with PCOS and the Interaction Between Dyslipidemia and Metabolic Disorder States: A Retrospective Study in Chinese Population

91 citations , July 2022 in “Frontiers in Endocrinology”

This study reported that Chinese women with PCOS exhibited diverse lipid profiles based on different characteristics, which may help understand their increased risk of cardiovascular disease.

research Higher PDCD4 expression is associated with obesity, insulin resistance, lipid metabolism disorders, and granulosa cell apoptosis in polycystic ovary syndrome

34 citations , February 2016 in “Fertility and Sterility”

This study suggests that higher PDCD4 expression may play a significant role in polycystic ovary syndrome pathogenesis through its association with obesity, insulin resistance, lipid metabolism disorders, and increased granulosa cell apoptosis.

research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity

24 citations , July 2018 in “Stem cells”

This study found that Runx1 in hair follicle stem cells modulates lipid metabolism, impacting membrane organization and enhancing signal transduction for cell proliferation in both normal and cancer epithelial cells.

research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function

22 citations , September 2011 in “Journal of Investigative Dermatology”

This study found that impaired TCF/Lef1 signaling in mice leads to significant skin barrier defects due to altered lipid metabolism and epidermal differentiation.

research Metabolic syndrome – a new definition and management guidelines A joint position paper by the Polish Society of Hypertension, Polish Society for the Treatment of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of Family Medicine, Polish Society of Lifestyle Medicine, Division of Prevention and Epidemiology Polish Cardiac Society, “Club 30” Polish Cardiac Society, and Division of Metabolic and Bariatric Surgery Society of Polish Surgeons

20 citations , August 2022 in “Archives of Medical Science”

This publication discusses the 2021 ESC Guidelines for the prevention of cardiovascular disease in clinical practice and reports no new results.

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community Physio-metabolic method (antiandrogen, minoxidil, leg training and cold)

in Treatments 309 upvotes 2 years ago

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

community Dear Dut users,have you noticed any metabolic changes with use of the drug?

6 upvotes 1 year ago

Dutasteride users have mixed results in hair loss treatment, with some experiencing improvements and others worsening. Some report metabolic changes like weight gain or diabetes, while others have no significant side effects.

community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

131 upvotes 1 year ago

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Anyone experienced weight gain on dutasteride?

5 upvotes 4 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

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