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Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

SHBG may be a useful early indicator and treatment target for PCOS.

Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.

Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Dermal adipose tissue in mice can change and revert to help with skin health.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Sex hormones, especially androgens, play a key role in causing acne.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Current treatments for androgenetic alopecia manage symptoms but don't cure it, and it affects social and psychological well-being.

Caffeine can protect scalp hair follicles from damage caused by UV radiation.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

Women with acne and PCOS should be checked for insulin resistance and related symptoms.

Fat-related cells are important for initiating hair growth.

Men with androgenetic alopecia have different scalp oils and microbes compared to those without.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Loss of oil glands and inflammation might contribute to the development of scarring hair loss.

Sebum helps protect human skin from microbes.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Sex-determining genes may affect male baldness.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.

Sebaceous glands play a key role in skin health and conditions like acne.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.