Scalp Microbiome and Sebum Composition in Japanese Male Individuals with and without Androgenetic Alopecia

October 2021 in “ Microorganisms ”

Kazuhiro Suzuki, Mizuna Inoue, Otomi Cho, Rumiko Mizutani, Yuri Shimizu, Tohru Nagahama, Takashi Sugita

androgenetic alopecia sebum triglycerides palmitic acid Malassezia restricta Cutibacterium Corynebacterium scalp dysbiosis AGA scalp oil scalp fungus scalp bacteria

TLDR Men with androgenetic alopecia have different scalp oils and microbes compared to those without.

The study analyzed the scalp microbiome and sebum composition of 118 Japanese males, comparing those with androgenetic alopecia (AGA) to those without. It found that individuals with AGA had higher levels of sebum triglycerides and palmitic acid, and their fungal microbiome was dominated by Malassezia restricta. The bacterial microbiome in AGA patients showed increased Cutibacterium and decreased Corynebacterium, indicating scalp dysbiosis. These findings suggest that both sebum composition and microbial imbalances may play roles in the development of AGA.

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Research cited in this study

13 / 13 results

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Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

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community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

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community 23-M Using minox and fin everyday also consulted dermat he just said androgenetic alopecia and gives 2 serum for dandruff which is quite visible in scalp more like it's settled on scalp and when I scratch I found this

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A 23-year-old male uses minoxidil and finasteride daily for androgenetic alopecia and is concerned about dandruff, which a dermatologist addressed with two serums. He uses ketoconazole shampoo twice a week to manage scalp issues.

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research Scalp Microbiome and Sebum Composition in Japanese Male Individuals with and without Androgenetic Alopecia

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research Comparison of Healthy and Dandruff Scalp Microbiome Reveals the Role of Commensals in Scalp Health

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