Microbiome in the Hair Follicle of Androgenetic Alopecia Patients

    May 2019 in “ PLOS ONE
    Bryan Ho, Eliza Xin Pei Ho, Collins Wenhan Chu, Srinivas Ramasamy, Mei Bigliardi-Qi, Paola Florez de Sessions, Paul L. Bigliardi
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    TLDR Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.
    This study analyzed the microbiome in the hair follicles of patients with androgenetic alopecia (AGA) and found that there were distinct microbial populations in the middle and lower portions of the hair follicle. The study also found that there was a higher abundance of Propionibacterium acnes in miniaturized hair samples from AGA patients, which may be associated with elevated immune response gene expression in the hair follicle. The study suggests that the microbiome may play a role in AGA pathogenesis and that further research is needed to understand the relationship between the microbiome and hair loss.
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