Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities

Research cited in this study 72

1. Sebaceous Lipids Are Essential for Water Repulsion, Protection Against UVB-Induced Apoptosis, and Ocular Integrity in Mice Development · 2016
2. Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2015
3. Expression of Dermcidin in Sebocytes Supports a Role for Sebum in the Constitutive Innate Defense of Human Skin Journal of Dermatological Science · 2015
4. Lipid Droplets And Associated Proteins In Sebocytes Experimental Cell Research · 2015
5. Ceramide Synthase 4 Regulates Stem Cell Homeostasis And Hair Follicle Cycling Journal of Investigative Dermatology · 2015
6. Deciphering the Functions of the Hair Follicle Infundibulum in Skin Physiology and Disease Cell and Tissue Research · 2014
7. BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor Under Steady-State Conditions Stem cell reports · 2014
8. Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis Journal of biological chemistry/˜The œJournal of biological chemistry · 2014
9. Ceramide Synthase 4 Deficiency in Mice Causes Lipid Alterations in Sebum and Results in Alopecia Biochemical Journal · 2014
10. Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands Molecular and Cellular Biology · 2014
11. Keratin 79 Identifies a Novel Population of Migratory Epithelial Cells That Initiates Hair Canal Morphogenesis and Regeneration Development · 2013
12. A Practical Guide for the Study of Human and Murine Sebaceous Glands In Situ Experimental Dermatology · 2013
13. Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis Journal of Investigative Dermatology · 2013
14. Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development Science Signaling · 2013
15. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update Journal of Dermatological Science · 2012
16. Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability During Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1 Journal of Investigative Dermatology · 2012
17. Primary Cicatricial Alopecia: Recent Advances in Understanding and Management The Journal of Dermatology · 2011
18. TCF/Lef1 Activity Controls Establishment of Diverse Stem and Progenitor Cell Compartments in Mouse Epidermis The EMBO Journal · 2011
19. Normal Fur Development and Sebum Production Depend on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands Journal of biological chemistry/˜The œJournal of biological chemistry · 2011
20. Keratinocyte-Specific Ablation of the NF-κB Regulatory Protein A20 (TNFAIP3) Reveals a Role in the Control of Epidermal Homeostasis Cell death and differentiation · 2011
21. Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv · 2011
22. The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling Development · 2011
23. Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
24. C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin PloS one · 2010
25. Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
26. Epigen Transgenic Mice Develop Enlarged Sebaceous Glands Journal of Investigative Dermatology · 2009
27. Corneodesmosin Gene Ablation Induces Lethal Skin-Barrier Disruption and Hair-Follicle Degeneration Related to Desmosome Dysfunction Journal of Cell Science · 2009
28. New Developments in Our Understanding of Acne Pathogenesis and Treatment Experimental dermatology · 2009
29. The Disruption of Sox21-Mediated Hair Shaft Cuticle Differentiation Causes Cyclic Alopecia in Mice Proceedings of the National Academy of Sciences · 2009
30. Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells Molecular biology of the cell · 2008
31. Hedgehog Signaling, Keratin 6 Induction, And Sebaceous Gland Morphogenesis American Journal Of Pathology · 2008
32. Dlx3 Is a Crucial Regulator of Hair Follicle Differentiation and Cycling Development · 2008
33. Smad4-Dependent Desmoglein-4 Expression Contributes to Hair Follicle Integrity Developmental Biology · 2008
34. Etiology of Cicatricial Alopecias: A Basic Science Point of View Dermatologic therapy · 2008
35. Targeted Transgenic Expression of the Mutation Causing Hutchinson-Gilford Progeria Syndrome Leads to Proliferative and Degenerative Epidermal Disease Journal of Cell Science · 2008
36. The Development of Several Organs and Appendages Is Impaired in Mice Lacking Sp6 Developmental dynamics · 2008
37. Mutations in the Helix Termination Motif of Mouse Type I IRS Keratin Genes Impair the Assembly of Keratin Intermediate Filament Genomics · 2007
38. Co-Factors of LIM Domains (Clims/Ldb/Nli) Regulate Corneal Homeostasis and Maintenance of Hair Follicle Stem Cells Developmental biology · 2007
39. Neuregulin3 Alters Cell Fate in the Epidermis and Mammary Gland BMC developmental biology · 2007
40. Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss Cell Stem Cell · 2007
41. Obesity Resistance of the Stearoyl-CoA Desaturase-Deficient (Scd1 -/-) Mouse Results from Disruption of the Epidermal Lipid Barrier and Adaptive Thermoregulation Biological Chemistry · 2007
42. The Role of Fibroblast Growth Factor Receptor 2b in Skin Homeostasis and Cancer Development The EMBO Journal · 2007
43. Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development Developmental Cell · 2006
44. Rac1 Is Crucial for Hair Follicle Integrity but Not Essential for Epidermis Maintenance Molecular and Cellular Biology · 2006
45. Hairless Triggers Reactivation of Hair Growth by Promoting Wnt Signaling Proceedings of the National Academy of Sciences of the United States of America · 2005
46. Two Mouse Mutations Mapped to Chromosome 11 with Differing Morphologies but Similar Progressive Inflammatory Alopecia Experimental Dermatology · 2005
47. Ectoderm-Targeted Overexpression of the Glucocorticoid Receptor Induces Hypohidrotic Ectodermal Dysplasia Endocrinology · 2005
48. Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling ˜The œAmerican journal of pathology · 2004
49. Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors Development · 2004
50. Morpho-Regulation of Ectodermal Organs ˜The œAmerican journal of pathology · 2004
51. Loss of Keratin 10 Is Accompanied by Increased Sebocyte Proliferation and Differentiation European journal of cell biology · 2004
52. A Small Deletion Hotspot in the Type II Keratin Gene mK6irs1/Krt2-6g on Mouse Chromosome 15, a Candidate for Causing the Wavy Hair of the Caracul (Ca) Mutation Genetics · 2003
53. Expression of Cyclooxygenase Isozymes During Morphogenesis and Cycling of Pelage Hair Follicles in Mouse Skin: Precocious Onset of the First Catagen Phase and Alopecia Upon Cyclooxygenase-2 Overexpression Journal of Investigative Dermatology · 2003
54. Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis Development · 2003
55. Phospholipase Cδ1 Is Required for Skin Stem Cell Lineage Commitment The EMBO Journal · 2003
56. Stimulation of Ectodermal Organ Development by Ectodysplasin-A1 Developmental Biology · 2003
57. Evidence That Myc Activation Depletes the Epidermal Stem Cell Compartment by Modulating Adhesive Interactions with the Local Microenvironment Development · 2003
58. Expression of Enhancing Factor/Phospholipase A2 in Skin Results in Abnormal Epidermis and Increased Sensitivity to Chemical Carcinogenesis Oncogene · 2003
59. Curly Bare (Cub), a New Mouse Mutation on Chromosome 11 Causing Skin and Hair Abnormalities, and a Modifier Gene (Mcub) on Chromosome 5 Genomics · 2003
60. Impaired Hair Follicle Morphogenesis and Cycling with Abnormal Epidermal Differentiation in Nackt Mice, a Cathepsin L-Deficient Mutation American Journal Of Pathology · 2002
61. Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles Journal of Investigative Dermatology · 2002
62. Cyclooxygenase-2 Overexpression in the Skin of Transgenic Mice Results in Suppression of Tumor Development PubMed · 2002
63. Expression of ΔNLef1 in Mouse Epidermis Results in Differentiation of Hair Follicles into Squamous Epidermal Cysts and Formation of Skin Tumors Development · 2002
64. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables Experimental dermatology · 2001
65. Deregulated Expression of c-Myc Depletes Epidermal Stem Cells Nature Genetics · 2001
66. Abnormal Differentiation of Epidermis in Transgenic Mice Constitutively Expressing Cyclooxygenase-2 in Skin Proceedings of the National Academy of Sciences · 2001
67. C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny Current Biology · 2001
68. Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia ˜The œAmerican journal of pathology · 2000
69. A New Mutation Rim3 Resembling Re Den Is Mapped Close to Retinoic Acid Receptor Alpha (Rara) Gene on Mouse Chromosome 11 Mammalian Genome · 1998
70. Harlequin Ichthyosis (ICHQ): A Juvenile Lethal Mouse Mutation with Ichthyosiform Dermatitis PubMed · 1997
71. Modulation of Murine Hair Follicle Function by Alterations in Ornithine Decarboxylase Activity Journal of Investigative Dermatology · 1996
72. Meibomian Gland Changes in the Rhino Mouse PubMed · 1988