BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor Under Steady-State Conditions

    September 2014 in “ Stem cell reports ”
    Kai Kretzschmar, Denny L. Cottle, Giacomo Donati … Fiona M. Watt
    Studysummary In this study, BLIMP1 was found to function in terminally differentiated epidermal cells to maintain homeostasis, rather than defining a sebocyte progenitor population.
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    Research cited in this study 14

    1. Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin Cold Spring Harbor Perspectives in Medicine · 2014
    2. Plasticity of Epithelial Stem Cells in Tissue Regeneration Science · 2014
    3. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    4. Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche Nature Reviews Molecular Cell Biology · 2013
    5. C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis Cell reports · 2013
    6. Development and Homeostasis of the Sebaceous Gland Seminars in Cell & Developmental Biology · 2012
    7. C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin PloS one · 2010
    8. Epidermal Stem Cell Diversity and Quiescence EMBO molecular medicine · 2009
    9. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009
    10. Dynamic Regulation of Retinoic Acid-Binding Proteins in Developing, Adult, and Neoplastic Skin Reveals Roles for β-Catenin and Notch Signaling Developmental biology · 2008
    11. Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis Development · 2003
    12. Expression of ΔNLef1 in Mouse Epidermis Results in Differentiation of Hair Follicles into Squamous Epidermal Cysts and Formation of Skin Tumors Development · 2002
    13. C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny Current Biology · 2001
    14. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989

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