research Theory and Practice of Lineage Tracing
This review discusses the principles, methods, advantages, and limitations of lineage tracing in stem cell and developmental biology but does not report new findings.
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research Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts
This study describes a method for labeling and tracking hair follicle stem cells in mouse skin using a Cre/lox recombination system with tamoxifen, providing insights into stem cell behavior and contribution to tissue regeneration.
research Genetic lineage tracing in skin reveals predominant expression of HEY2 in dermal papilla during telogen and that HEY2+ cells contribute to the regeneration of dermal cells during wound healing
In this study, researchers discovered that HEY2+ dermal papilla cells exhibit stemness and contribute to dermal regeneration during wound healing, as shown by the expression of a reporter gene in regenerated dermal cells of tamoxifen-induced transgenic mice.
research Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin
This review highlights recent advances in CRISPR-based lineage tracing methods that can improve our understanding of skin stem cell behavior, regeneration, and disease, with potential applications in organoids and model organisms.
research Discovering New Progenitor Cell Populations through Lineage Tracing and In Vivo Imaging
This review discusses the evolution of lineage-tracing strategies over the past century, emphasizing their role in identifying progenitor cells and resolving debates about cellular origins, with no new results reported.
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